Latest BIOS v1.80, installed an SSD, HDD and ODD to ports 1, 2, and 4, respectively. NVME drive as boot is OK. Has been running perfect for about 3 weeks until suddenly BIOS doesn't recognize the SATA3 drives anymore. Tried clearing CMOS and flashing the BIOS with no change. Tried replacing SATA and power cables same results. As example the ODD has power, so I assume the SSD and HDD have too. Any help appreciated.
Those parts should work together. Do you have "AMD StoreMI" enabled?
Have you tried booting with the mechanical HDD disconnected, just to see if that make any difference?
Have you tried switching the Adata SSD to the 2nd M.2 socket to see if that make any difference?