Where are intel or AMD with their true "System on a chip"?
Modem, lan, wifi controller, audio chip, all on die with the cpu, in such a way that they can get rid of all those externa; controllers, sucking up power, and using up valuable latency!
Audio applications could go so much faster with dedicated hardware built directly into the CPU ring (like VST's could work better). Latencies could be reduced not only from audio, but also networking latencies; which are currently the biggest issue for slow working webpages!
And although creating a massive chip that will replace 90% of onboard hardware, will result in slightly worse CPU performance, it might increase program response (programs that are depending on internet, audio connections, etc...); plus Intel or AMD could not only create all these chips at 32-20nm, but also powergate them, making them so much more energy efficient!