On the SSD, keep your OS, Browser, Office, Driver, Media Players... and programs you want to benefit with a faster startup... and then install all your games and regular programs on the other drive. It's best to create a folder and call it something like Game Installs or Program Files (if you want to use that name).
Also, contrary to what some others might say... I find it works great of you simply relocate the following folders: Downloads, Music, Videos, Picture, Saved Games to another drive. It's great because if your OS drive crashes or you need to reinstall... you don't have to worry about saving or losing your data.