I like the layout of Chrome, but the problem is that it freaks out after a while with flash apps. However, this could be because of the lack of the IT department updating the software here at my school, which is where I use chrome. For the past few years, I have been hooked to Firefox, it has all I need. As far as IE, it has behind the rest of the browsers. When IE comes out with something people call "new" it is most likely something borrowed off the other browsers, but with Microsoft's own spin (ie: tabbed browsing). I use IE only for the sites that don't like Firefox (a number that is decreasing at a substantial rate). One problem with Firefox though is it does use a good bit of resources, but they are trying to optimize their browser and the GPU acceleration will be a great benefit.
Sorry Opera, you just have been out of the game long before I switched off of IE.