Question Can i use 1x16gb corsair vengeance RAM with 2x8gb corsair vengeance?

sure you can but they could met a problem when XMP state
RAM with different ratio, but same ddr standard can work together (usually your MOBO only support one ddr standard), but their Operating Frequency will follow the lower
for example
you cannot mix ddr3 with ddr4
when mix 2133MHZ ddr4 and 2400MHZ ddr4, the default operation frequency will be 2133MHZ
Also it is very very very hard to OC
And you might lost daul channal