I'm building a mining rig with two GPUs (And hopefully 3 at some point), but the motherboard won't boot if two GPUs are in. If I put only either one in, it boots fine. My motherboard is from a XW4400 workstation, and has 4.5GB of DDR2 with a Q6600. It has 3 PCIE slots, an x16, an x4 with x16 size and an x1. I've tried using a riser in the x16, and using an x1 to x16 adapter in that slot. Everything works fine with one GPU, it POSTs and goes to OS. The GPUs I'm using are a GTX 980 and GTX 660. The correct PCIE power connectors have been plugged in, and a molex to the x1 to x16 adapter board when used.