back then I was coming from AM3+ so had to buy DDR4 ram and a processor along with the motherboard so was a little short on budget when it came to the mobo but so far it has served me well though with MSI's BIOS updates stability grows questionable.
I think it pretty safe to assume it won't be any different from my son's B450m Mortar. I upgraded my system to a 5800X (it's a B550m TUF gaming plus) and moved the 3700X into his Mortar.
On the latest BIOS it's amazingly good with the 3700X strung out using a fully tweaked PBO and 3600 memory. As far as memory goes, I just bought a GSKill Ripjaws 3600 rated kit and enabled XMP with no problems. We worked at it a bit and were able to tighten up some of the timings quite a bit too.
I think you should be fine if you are careful and work methodically. Most people jump in with random BIOS settings without even resetting CMOS after updating or swapping hardware so it's hard to gauge actual results from their experience.
ADDED: But to be honest, the actual changeout wasn't without some grief. After first replacing the processor (it was already on the latest BIOS) and resetting CMOS it booted to BIOS just fine but refused to go into Windows when secure boot was enabled...it would just hang up at the spinner. I had to reinstall the 1700 then enter Windows and disable all the security, change to using a password instead of PIN (even though the PIN wouldn't work anymore) and clear TPM storage. Then swap the CPU, reset CMOS again, enable UEFI and secure boot and it would get into Windows with standard security again. What a mess!
I don't know what it's all about, maybe just additional complications with the new Windows updates and TPM enabled by default in BIOS maybe, but that seemed to work for me. I was thinking I'd have to do a clean install of Windows to get set up with new security lockouts.