jpishgar :
While it is installed, Skyrim will not work
It is important to understand that
it is worth it.
-JP
If you're not using Mod Organizer, you should be. MO doesn't "install" mods into your Skyrim installation like other mod managers do. It installs them in its own directory. It even moves save games into its own directory (under different "profiles" so you don't have to have saves for multiple characters mixed together). When you launch the game with MO, it creates a virtual instance of the game override directory with the selected mods active and runs the game there. This means you can
instantly turn mods on and off and start the game. No need to install or uninstall a mod every time you want to run with/without it.
Enderal installs assuming you're using a regular Skyrim install (or regular mod manager), which complicates this a bit. But it is possible to set it up in Mod Organizer so you can quickly flip between Enderal and regular (modded) Skyrim using Mod Organizer.
https://www.youtube.com/watch?v=C74LjT96pr0
I wasted hours installing and uninstalling mods with Nexus Mod Manager, waiting the entire install/uninstall process while I was trying to figure out which mod or mod order was causing crashes or problems. Then I discovered Mod Organizer, which lets you do this sort of install/uninstall or reordering instantly. It takes a bit more effort to learn how it works, but once you do it's so much simple, cleaner, quicker, and more flexible.