U can only mount GPU in one way, with the fans on the underside of the card when mounted. Those fans are blowing the air upwards through the GPU.
The fans in the bottom should blow air into the case.
The fan in the back should blow the air out of the case.
Then you have the ability to mount 3 fans up top, these fans are mounted vertically instead of horizontally (like in most other cases that have top mounted fans). These fans should be mounted so that the air blows out of the case. Here you can also choose 2 different ways to mount the PSU, either you mount it so that you can see the PSU-fan from inside the case or you can mount it so that the fan is on the other side.
If u google on your case you see what i am talking about. I am at work right now so i can not draw a picture for you.
May i ask about your temps?