I can't just use 1 browser. No 1 browser does everything. Chrome is far more refined than it was 4 years ago, but it is often still unstable, and unable to properly render web pages.
I find myself juggling between FF for work, Chrome for play, IE only when absolutely necessary, and Opera as backup. Of all of those, only Opera feels like a completely self contained system that is always ready and waiting for me, as opposed to all the others that feel somewhat detached and session-centric.
I leave Safari on my computer too, but only if every other browser is somehow not working...
Bravo to Chrome for pushing FF and IE to streamline and promote stability, as FF had been flailing for a while between 3.5 and 3.6, and IE was unmitigated disaster after disaster until IE9...
Opera still owns my mobile web completely, only occasionally being supplanted by Dolphin when there is a glitch.