How did you calculate the 250w of the build?
Assuming it's correct the calculation, the 300w will be just enough for 250w build, but the psu will always work within the upper range of operability capacity and will allow less room for eventual upgrades (additional HDDs, cards, etc.)
It also means that you might have shorter lifespan of the psu, although i believe it has negligible impact...
Performance of the build will not be affected; however the stability depends on the quality of the PSU.