That hole in the front of the case is designed for access to mount two accessory devices, probaly in the standard 5¼" size, like optical drives. The upper one is partially blocked by an interior metal plate that probably can be removed. To do the installation, you probably have to remove the front panel.
The holes inside in your second photo is where you could mount a fan It looks like it would draw air from inside the front panel, and it appears to be located behind the On / Off switch on the front. To make that work there would need to be air intake gaps between the front panel and this interior mounting plate, plus some way to use foam air dust filters on that intake.