opps. i just reread and see it's a laptop (sorry), it should already be enabled after all, it's hardwired. laptops make it tricky, the power button is probably for hibernating and NOT turning it off.
To get into the bios:
Toshiba 335 CDS: ESC
Toshiba Protege: ESC
Toshiba Satellite 205 CDS: F1
Toshiba Tecra: ESC then F1 or F2
Toshiba Notebook [Newer models]:
Turn on the computer by holding down the power button while pressing the ESC key
The machine will beep, then display:
Check System, then press [F1] key.
Release the ESC key
Press the F1 key
If the keyboard is not working in bios, that's a problem. In that case, you need an external keyboard. (aka there is a problem with the on-board keyboard). If it works in bios, in theory it should work in safe mode, unless the drivers are not being loaded somehow. Again try an external keyboard.
NOTE: since you are stuck in safe mode, try the external keyboard trick. it should load the drivers even in safe mode and allow you to reboot.