Hello... when your reset/clear the BIO"s... It goes to "Default settings" anything set "special" before was LOST.
So... 1) You need to first BOOT thru the MB/CPU/IGT Video connector to your monitor... that is "Default" for display with your MB.
2) SET the MB BIO's for IGT PCIe ONLY or BOTH before using it for your Display needs, Save&exit
3) Un-plug PS from wall.
4) Plug in your exterior Video card, and cable, and monitor setting with it.
5) plug PS into wall.
6) Bootup
As your fore mention question...
To the MB BIO's they are treated as two separate hardware devices and can report back if one is not active... By default your CPU/IGT will be made active and a graphic fault will NOT be reported. You can TEST all your Video Card Outputs while the computer is on to see what is active... Just be carful plugging in each time and de-power/Power, the monitor, between tests.
As TOO memory, it will TRY to set 1333, 1600 Dual channel as default, this is a safe setting to get the computer to boot... the Mem controller is on the CPU and has a Spec set for it. If the MB/CPU fails to get a sync with your memory it should NOT BOOT, and report back some way (beep code).