I can't, though I do get lazy and forget about the clutter. My PC at home is clean for now. But that depends on the work I do on it. Sometimes I put files on the desktop temporarlily and it can get cluttered at time that way.
I tend to use the Quicklauch icons for all my apps, but with my 19' monitor and 1280x1024 that fills up fast too.
I agree though, Fuse's desktop would drive me nuts.