Complete waste of money. In fact, if you added a third GTX 580 it would just be sitting there causing noise and heat and not really contributing to any rendering whatsoever, so for a fourth to be there...
In fact last night when I was busy gaming away with my two GTX 580s I'm pretty sure that I could have easily fried an egg on the back of my case it was so hot. Had to set the fans to run faster and temperatures came down by 15 degrees celcius or so.
Also, not many games will support anything more than 3-way SLI. It's honestly just an all-round waste of money. People that do it are just