The Baldur's Gate series (Baldurs gate 1&2, Icewind Dale, Neverwinter Nights series) may be old classics, but the Enhanced editions bring them a little more forward into modern resolutions and are worth checking out.
Planescape Torment is in the same vein and also worth checking out, as well as Arcanum Steamworks
Anachronox is also old, very different. Def one of a kind. Slow starting, but gets better.
SpecOps, the Line. Shooter with mind Fvckery
Remember Me.
The Book of Unwritten Tales
Valkyria Chronicles