You already only need one wire pair at 12V... if you make it #6 solid or #4 fine-stranded for flexibility.Of course doubling the voltage to 24V would reduce the heating load by the factor of 4 and further quadrupling to 48V to the factor of 16 so that the whole power could be easily supplied by just a single (!) wire but here is one issue.
Imagine using rigid-wiring for GPU support
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