I've had trouble with Soyo boards and WCPuid in the past as well. Just seems that some are incompatible. I was using it to make my temps a little cooler on some systems, but after applying the changes, a couple of them would sound like they were shifting gears and then just lock up. Most systems had no problem, just a couple that had Soyo KT7-Dragon boards with 1800+ CPUs (Palomino core).
-Brett