Disclaimer: Results vary of course from chip to chip and mainboard to mainboard, and some poor folks have indeed ruined their mainboards and/or cpus during overclocking endeavors....; MSI mainboards included, so proceed at your own risk.
The 90 nm Venice cores will usually make 2.4-2.5G without little fanfare, and your MSI PLatinum is no slouch;
Jump into BIOS, set HTT to 3x or 4x (some like my own K8N Neo4 do not seem to like the 4xHTT setting, despite it being well under 1000 MHz total, but do OK with 3x setting; I'd prob start there, alhtough technically the 4x setting should be fine up through a 250 Mhz FSB)
DDR voltage: adjust form stock 2.6V to 2.7V if you think you might be exceeding 200 MHz speeds....
NF4 voltage: Adjust from 1.4 to 1.45 or 1.5 Volts
Mem clock...
Set mem freq to manual, adjust freq downward to (depending on BIOS version) 166 MHz form it's stock 200 MHz...
CPu core voltage: change from "auto" (1.4 v) to manual, and set for 1.5V initially, you can check for stability at lower voltage points later, if mb is stable at elevated FSB levels...
Adjust fsb in core cell menu within advanced chipset features section, set for 210-215 MHz initially, and if stable in POST, Windows boot-up, and Prime95 and a few FEAR timedemos, you can then shoot for 220, 230, etc....(your mem, if set at 166 base clock, will be running back at it stock 200 MHz once you are at 234 MHz FSB; depending on your BIOS version, you might have base mem clock selections of 100, 133, 166, 200, 220, 233, and some older BIOS versions have 150 MHZ and 180 MHz base clocks available as well. I wouldn't try for much higher than 200-210 MHz unless you know your mem will handle it)
(Your cpu temp will prob jump from 40C to about 46-48C under full load, which would be fine assuming the system is stable)
With a stock 9x multiplier (can only be adjusted downwards, which is prob unnescessary for your cpu), and if you can hit 245 MHz FSB, you would be at 2.2G, and approx at 3500+ performance levels...; if your particular mb is stable at that 245 FSB, you can go upwards in FSB adjustments at your own risk, carefully monitoring cpu temps, and of course, stability during Prime95 and 3d gaming scenarios...
(many K8N Neo-4 Platinum mainboards are stable up to 280-300 MHz FSB or higher, running lower mem clocks to keep mem freq at or near 200-220 MHz; as you have 4 sticks installed, I'd prob try to keep your base clock so that it does not exceed 200-210 MHz after the OC...)
If you visit the OC /mainboard section in these forums, there are areas devoted entirely to MSI mainboards, as there are a lot of adjsutments to allow you to loosen your mem timings for an even higher FSB, although I personally prefer to simply adjust for a different ratio/base mem clock, keeping relaitvely stock timings)...
(In the event you overdo it, and have a NO POST result, do not panic, as there is a convenient BIOS reset switch on MSI mainboards which will set quickly set you back to factory defaults...)