I've been perpetually juggling space on my Hard Drive for games, so I finally purchased a 1 TB Caviar Black, which in turn let me finally test out additional operating systems (I've been on XP 32 bit for years).
Installed Windows 7 7077 64-bit, haven't had a single crash, haven't had a single driver give me any issues.
The only problems I had was with running Bioshock with Directx 10 shaders. I could play the game fine, swim to shore, get into the sub to go to rapture, and it would just freeze at that loading screen.
Once I disabled the shaders, loaded into the game, I was able to re-enable them and its been fine ever since.