All signs point to Comodo, but it is what it is. Thank you for sticking with this post this long. Persistence is key.
I have two more ideas, short of going blank slate which you probably will not want to undertake just for one misfit program.
Option 1: Perform a system restore. This is Windows equivalent to Time Machine found in Mac OSx. I do not know how frequent you programmed your restore points, but by default a restore point should be created after a major change to system is made. In your case, this will be the installing of Comodo or any other program you may have missed between the time WLM was working and not. Start with the nearest date you recall WLM working as it should. Do not worry all your documents, files, folders will be preserved.
An excellent and short guide from Windows on performing System Restore:
http://windows.microsoft.com/en-us/windows7/products/features/system-restore
Option 2: Use an alternative program that is arguably less temperamental. My choice is Thunderbird.
Here is a excellent guide to migrate from WLM to Thunderbird, step by step:
https://support.mozillamessaging.com/en-US/kb/switching-thunderbird
I know Option 2 sounds like a cop out and going around the problem, but better software in my opinion is as good as any solution especially one that requires tweaking the existing software to make it work. Going through the forums you'll see your problem with WLM is echoed from a lot of users.
While I have a few other ideas (I'm never really out of them, a curse and blessing to a stubborn nature) it's hard to explain unless I am physically able to work on the computer. Regardless, Option 2 will most certainly allow you to resume checking mail as you used to. Option 1 is the Hail Mary, well technically reinstalling the OS is.
I'm sorry I am not able to help you any further. My last helpful gesture of goodwill is bumping your post up when I submit this reply. Hopefully someone more knowledgeable than I will come to your aid. Good luck