So I got my RX480 4GB today and it's currently installed and under use.
Using Windows 7 64bit with an i7 2700K running at 4.6Ghz and 16GB of RAM pushing a 1080p@120Hz display, I don't notice a big difference in performance for most DX9 titles I play, except when I see the FPS numbers ("feeling" vs "numbers"). For example, in GuildWars2, I saw a massive improvement in the new maps, where they use more shinny effects (from stuttering to no-stuttering; most welcome change) and everywhere else, the FPSes were higher: 50-60 to 90-100, but you really don't notice it that much. Testing out American Truck Simulator (don't ask xD) I saw almost no change, so I am guessing the engine must have a bottleneck somewhere; for this one, I have to go downstairs and use my G27! Well, more of that over the weekend xD
I am yet to test DOOM and the other titles I have, but so far the increase in performance over my 7970Ghz is good.
In terms of visual appearance, I have to say it's one handsome card. My Vapor-X was good looking, but standing next to the Nitro+ looks bad. The pictures don't make the card justice, really. The black is matte and the backplate is not extra shiny. Plus the fine-job on the corners of the cooler is just great.
Oh, and one thing I didn't notice until I actually held it: the 8pin is at the back of the card, not at the top (side top?). It might be a bother when you have little room on the back (between MoBo and HDD area for most cases), but the Vapor-X was longer (~1.5 inches longer) than the Nitro+, so even with the 8pin on the back it fits fine.
All in all, holding its value for now.
Cheers!