I think the icons are being automatically rearranged.
https://windows.tips.net/T006814_Arranging_Desktop_Icons_Automatically.html
If the above does not resolve the problem there are still other things you can do:
Double check what all is being launched at startup and consider that some customization by an app may be happening. Or maybe some tool or control panel that got installed.
Take a look at gaming and keyboard settings via "WIN" + "I" > Gaming and also "WIN" + "I" > Keyboard.
Mostly as a matter of elimination if nothing else.
GPU: Go to the manufacturer's website to download, reinstall, and reconfigure the GPU drivers.