Check the connection between the mobo usb header to the pump head.
Also may try another usb header.
Check in device manager look for any unknown items that needs enabled or a driver.
Look in the usb sections at every item.
I have had issuse's where i had to enable the device to show and control fan and pump speeds.
If dev man doesn't show anything wrong
Rerun install software it should take you to the unistaller, it might also ask if you want to remove config files click yes.
Uninstall then reinstall
Let us know what you come up with.