PSU is the most complicated since there is no single consumer grade PSU that can power all that alone. Highest consumer grade PSU is 1.6 kW (1600W), but each 3080 Ti is 350W, with 4x of them, you're looking 1400W. And CPU is power hungry as well, 280W. So, when we add the rest of the system to it as well, ~200W, total power consumption would be 1880W, ~1900W or 1.9 kW.
Now, there is one, 2 kW unit, EVGA SuperNova 2000 G+ (2000 W), but that runs only on 230V and if you're in USA, you can't use it. But if interested, then,
Amazon UK:
https://www.amazon.co.uk/EVGA-Power-Supply-Modular-Warranty/dp/B093Q9KBBP
Though, you'd be much better off buying two PSUs, where 2nd PSU is used to power 3 GPUs. E.g two 1.2kW PSUs, where 1st powers CPU, MoBo and one GPU, while 2nd, 1.2kW PSU powers remaining three GPUs.
Further reading about good PSUs to choose from,
link:
https://techguided.com/the-best-gaming-power-supplies/
(I use and suggest Seasonic, but you're free to pick your own choice.)
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With PC case, choice would only be full-tower ATX or even super-tower ATX, since only these two are big enough to house all that hardware.
I, personally, use Corsair full-tower ATX PC cases (2 in use) and i can vouch for the build quality. Corsair also offers super-tower ATX cases. Though, Thermaltake also offers super-tower cases and you may look towards Thermaltake instead, e.g Core W200,
specs:
https://www.thermaltake.com/core-w200.html
It's on wheels and it would be much easier to move around, since the PC will weigh a lot. Also, Core W200 has ample room for all that hardware + cooling, even if you go with AIO or open-loop cooling (to house all the radiators). Oh, Core W200 is dual-system PC case, where you can easily put two PSUs in, despite only having one system in it.
Though, do note that choosing a PC case is personal choice and feel free to pick the one that you like the most. But keep in mind that you may need to use two PSUs, so, look for two-system PC cases, if you want to house both PSUs in singe PC case.
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And as far as cooling goes, especially CPU, well, things get difficult.
Threadripper PRO uses sWRX8 socket and that is identical to that of the TR4 and SP3 sockets, so all CPU coolers that support TR4 and SP3 sockets, can be used on sWRX8 as well.
Though, i suggest looking into room ventilation, since if room doesn't have any ventilation and is small, PC will heat up the entire room, greatly reducing the components cooling.
Another option, would be keeping PC in another, well ventilated room and use it over LAN (e.g similar how servers are in the separate, well ventilated room, while servers can be used from anywhere).
you really should get liquid cooling for the cpu
You do know that AIO is still cooled by ambient air and it doesn't provide any cooling performance over conventional air coolers, right? All what AIO with rads does, is taking the heat from CPU block to rad, where rad is still cooled by ambient air.
In a non-ventilated room, only cryogenic fluids (e.g LN2) aren't dependent on ambient air and is an option for cooling, albeit those are very expensive and also very maintenance heavy.
For the case Ive always liked Meshify, for this i would say the meshify 2xl case
PC case is personal choice. You may like Meshify but OP may not. Also, any word about why you suggest Meshify 2XL, other than that YOU like it?
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