I wouldn't have a hard time spending that money, but of course I'm not a gamer.
MB + RAM + CPU should set you back over 1.000 if you choose it right.
Since you will probably go with SLI, 2 videocards easily another 1.000
2 TFT monitors at 23 inches a piece for the DVI's and a Nice bright Beamer for the S-video out will set you back around 2500 to 3000.
If you shop around for the latest of the latest keyboards, mice and other input devices you can easily total up another 500.
6 HD's at 300 Gigs a piece will add another 1000 minimum.
That's could total up to 6500 just for that, that's without an additional soundcard, case or PSU.
Now me, I'm no gamer and I'm not into the SLI thing, but I could easily find room for an E-MU1820, TV/FM-tuner, Webcam, HD plasma TV, fingerprint reader, printer and scanner or a multi-functional (a laser would do nice with money to burn), various types of fan or lighting controllers etc.
If you go with Watercooling, you won't even get there with 10.000. Just some ideas.