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Besides physically fighting with a tailgater, what's the largest calibur gun you have ever pulled on a tailgater and in what country/city?
I don't do road rage. It's just not worth getting worked up over some idiot high-school dropout with pee-stained pants driving his beater '83 Olds 88 two inches behind your bumper. It's not worth the time to stop, get out of my car, and get into a fight with the prick to beat some sense into him. It's certainly not worth getting hauled into the police station with assault charges, and if you have a real job, that actually looks bad (the prick doesn't care as he is probably living off my tax dollars anyway.) I ignore them if I am on a two-lane road and move over after passing the car in the slow lane (that's the only reason I am in the fast lane as I do know how to drive well) and let them pass if I am on a four-lane+ road.
The biggest gun I have ever shot would be my slug gun. It's a 12-gauge Remington 870 Express Magnum with a stubby 20" rifled barrel and a 3-9x40 scope. I shoot 3" magnum 385-grain slugs out of the sucker that have enough power to shoot through an engine block- the police use the same loads to do just that.
It kicks like a sonofagun but all it takes is one shot to drop whatever you are shooting. Most deer rifles this side of a .45-70 take a couple shots to guarantee that the deer is cleanly dispatched- my dad usually puts two or three shots from his ought-six into a deer before he's satisfied it won't go far.