This is essentially a duplicate thread, save for the compatibility question - which I've answered below.
10th gen is compatible with 400 series motherboards only.
8th and 9th gen is 300 series.
If you're feeling adventurous, and want to pair a 3080 with that psu anyway - good luck.
The CX750 won't blow up on you, but should you run into crashing, you'll have to do one extra step of troubleshooting besides the usual driver-related stuff... and the only way to troubleshoot psus is with another psu.
The crashing is yet to be completely determined:
-Hardware? The whole POSCAPs VS MLCC debacle.
-Early drivers? Well, it is a new architecture, after all...
-Software? Vendors and users are apparently pushing too high core clocks