The conservative advice is to do a new clean install.
But, many times we have so many apps and games installed, as well as a number of settings that would be a pain to recreate.
If you are in that situation, like I have been recently with my own pc, and with several of my kids pc's, then give it a try.
First, protect yourself.
What I do is take a cloned image of the current running C drive on a ssd of whatever size you need.
It is easy with samsung and their ssd migration app.
Then, use that cloned image alone and try to boot to the new cpu and motherboard.
My experience has been good for about half a dozen such upgrades. If you can boot, install the new chipset and other motherboard drivers. They have all been intel to intel.
I...