Which Model O mouse: wired, wireless? (You mentioned "plugged into my PC" so wired is the likely connection via a USB Port.) What else, if anything is plugged into any adjacent PC USB ports?
Laptop, headphones - make, model, connectivity? USB or 1/8"(3.5mm) jack?
When a static charge builds up, the electrons will find a path to escape to ground (earth) and flow accordingly. If that flow path goes through the mouse in some manner then the mouse LED's could light up.
And you are able to constantly and regularly create a static discharge and cause the mouse LED's to light up - correct?
Sketch out a diagram of your room showing all wires (power, audio, network, video, surge protectors, etc.) connecting your devices.
Key is to discover how the electrons are getting to the mouse. If that cannot be determined then something else is happening.
It's a wired model O mouse plugged into the PC via USB. There is also an rgb ducky mechanical keyboard plugged in via USB but I have never seen a similar problem with that. I also plug and unplug headphones (3.5mm) when needed next to the power button on the front of the case where my peripherals are plugged into the back. (Plugging in the headphones often causes the mouse rgb to light up as well.)
Yes, I am able to constantly recreate the static. Whether that's generating static on my bed, plugging in my headphones OR even plugging things in on outlets across the room. Also if I discharge my finger on the little screw on the light switch.
Maybe it's a really sensitive mouse?
https://ibb.co/jhvDNVP
Its a quick sketch of the room I'm not very good with diagrams, everything on the desk connected to one surge protector which is then connected to the wall outlet:
(PC, power supply, two monitors connected to gpu via displayport, USB rgb keyboard, USB Model O wired mouse, wifi antenna, headphones)
(Eero mesh wifi node also on desk connected to surge protector)
Nothing plugged in any other outlet. I could probably spend time on a really detailed sketch but I'm hoping this issue isn't too crazy in need of an analysis. All I can imagine is it travels through the power outlets but it's weird because when I plug in my headphones into my laptop which I put on the desk, the mouse lights up. (the laptop is on battery power so no connections) can electrons travel through the desk or something?