I had the same problem and spent many hours trying loads of different recommended fixes but nothing worked. Then I found at manufacture my 1tb hdd had been partitioned to create a C drive for the OS and a D drive for storage, in other words a virtual second drive with only one physical HDD. 165gb used on C and nothing on the D drive. Windows 7 had the free upgrade to windows 10. The fix that worked immediately was to go to disk management from start menu, delete D drive and expand C drive to max. Then open command prompt as administrator and typed in chkdsk /r /f and hit enter. Then restarted pc and let it do the rest. Did it for me after 3 days of trying fixes. I now have one 1tb C drive. no more 100% disk usage, no more freezing or unresponsive windows 10, chrome or edge. Boot up fine now and working best it has ever done. This will not work on a machine with 2 physical drives.