Set it to the XMP profile 1. Auto leaves everything up to the motherboard to determine what the settings will be. The XMP, A-XMP or D.O.C.P profile settings specifically determine what the speed, voltage, and primary, secondary and in some cases tertiary memory timings will be, and those timings are HIGHLY important in a specific memory kit being able to run without errors. Otherwise, a board will generally try to default to a fail-safe type setting that will offer a balanced combination of a safe setting and decent performance, but might in some cases be neither stable OR perform well.
Motherboards have gotten much better about training memory in a favorable manner, but they are not going to be as good as the XMP profile in most cases OR as good as manually tightening the timings yourself afterwards, if you should desire to do so, which then requires a good deal of stability testing to ensure that your manual settings are not going to lead to micro errors or instability.
I would update to the chipset driver version found on the AMD website, like I posted a link to. AMD and Intel generally have much newer, the latest, chipset driver versions available compared to what you will find on any motherboard manufacturers product page downloads. That is because THEY give those chipset drivers to the manufacturers in the first place, but those manufacturers don't always offer an updated version because it's usually more work for them to tailor or customize them in a way that makes offering it worthwhile as a model or brand specific offering. When it comes to chipset drivers I always recommend going with whatever the newest version is. Usually that is the version offered by AMD or Intel. Occasionally a manufacturer has a good reason to modify or update their version and if their version is newer then I recommend using that version or if there simply ISN'T a version offered to the public by AMD or Intel, then you don't have much choice besides using what your board manufacturer has on tap.
It would also be a good idea to make sure you download and install the most recent available driver version from your motherboard product page for the network adapter (LAN/Ethernet and for boards that have it, WiFi as well) and audio drivers. Most other motherboard specific drivers are already included in the chipset drivers.
In truth, if it were ME, I'd be looking to make a change to a higher end chipset motherboard like B450 or X470. Those B350 and A320 boards simply don't have as good of memory compatibility as newer chipset versions, even WITH BIOS updates in many cases. It's certainly not "essential", but I'd recommend doing so if you find you continue to have memory compatibility or weird little issues that you can't explain in any other way.
In truth, early on many of those chipsets and configurations wouldn't even run, AT ALL, unless you were are the baseline default of 2133mhz OR were running some form of Samsung B-die IC equipped memory kit. They've improved compatibility considerably, but it's still not as widely forgiving as say, most Intel platforms, or newer Ryzen chipsets, when it comes to memory.
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