Mass effect 3 doesnt need high end rig before you can play it. of course it would run on laptops... it would run even below the capacity of your own hardware....It runs flawlessly on my current rig @ 1920x1080. I recently purchased an Asus G74SX-XT1 and I'm very pleased on how it runs. I had some doubts with it being a laptop but with the GTX 560m, i7 Quad, SSD & 12GB of ram I had zero trouble with the game at full res.*
The only qualms I have with the game is the FOV but we dealt with it for the last two installments so it's not really a major problem for me.
*Got it on sale for 1,199.97.